College of Arts and Sciences Department of Biology
Omar Skalli, Ph.D

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Omar Skalli

Associate Professor, Director, Intergrated Microscopy Center

Ph.D.University of Geneva, Geneva Switzerland

Office: Life Sciences 103
Phone: (901) 678-1730

Other links:
Laboratory Web page

Integrated Microscopy Center

  • Cytoskeleton, with an emphasis on intermediate filaments and their interaction with actin filaments. We are especially interested in intermediate filament protein synemin and its binding to the actin filament bundling protein a-actinin.
  • Role of intermediate filaments in the motility of astrocytoma of cells. Astrocytoma cells express four intermediate filament proteins, including vimentin, nestin, GFAP, and synemin. We are examining the respective contributions of these proteins to the motility of astrocytoma cells as well as the mechanisms involved.
  • Involvement of intermediate filament proteins, and of synemin in particular, in P13K/Akt signalling.
  • Functional differences between a-actinin 1 and 4, two a-actinin isoforms differently regulated during brain development and critical for the motility and proliferation of normal and malignant neural cells.
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Last Updated: 2/4/13