Graduate Program: M.S. Thesis
I have always been fascinated by the human body. The astounding intricacies of our
anatomy are only mirrored by the profound physiological changes that even the smallest
mutations can elicit. Under the mentorship of Dr. T.K. Gartner I am studying Sickle
Cell Disease, one of the most common severe monogenic disorders in the world. Specifically,
we are looking at SCD's effects on bone. Our aim is to quantify the morphologies
induced by the disease in a mouse model by measuring bone mineral density and content.
In addition, we are running a drug trial to see if the effects can be mitigated over
a ten-week trial period. We have also recently endeavored to begin a project with
St. Jude's to screen several hundred compounds and assess their abilities to deter
hemoglobin polymerization. We hope that our findings will contribute to the pool
of knowledge about the disease and further progress in combating it.
Office Location: Life Sciences 311
Spring 2014 Office Hours
By Appointment Only