Organic Medicinal Chemistry--CHEM 4315/6315


Students to be served: This course serves as an elective for chemistry majors and minors, and may be of interest to students preparing for careers in research, medicine, dentistry, pharmacy, and related health professions.

Prerequisites: CHEM 3312 with a grade of at least C-.

Course Description: Introduction to principles of medicinal chemistry; structure, synthesis, and biochemical mechanism of action of major drug classes. Three lecture hours per week.

Textbook and other materials:

  • The Organic Chemistry of Drug Design and Drug Action, 2nd edition, author: Richard B. Silverman

Course Objectives: To provide students with understanding of and experience in the practice of medicinal chemistry.

Course Outline: This course focuses on medicinal chemistry and the underlying principles from organic chemistry. Topics to be covered include drug discovery, lead modification, drug-receptor interactions, enzymes, DNA structure and drug interactions, and drug metabolism.

Grades:  A comprehensive final examination will be administered in class at the assigned time. At least one test will be administered in class and graded before the last day to drop. Other tests, quizzes, and graded assignments, weighting, and grade ranges are at the discretion of the instructor and will be detailed on a syllabus distributed on the first day of classes or posted on eLearn.


  • Tardiness and unexcused absence from class are unprofessional behaviors which should be avoided, but attendance will not be graded.
  • Electronic devices such as cell phones and pagers should be turned off in the classroom.
  • Reasonable and appropriate accommodations will be made for students who present a memo from Student Disability Services.

Instructor Homepages
Dr. Abby Parrill

 On-line Resources