Dr. Esra Roan Awarded 2013 Junior Investigator Award
Dr. Esra Roan, Assistant Professor in Biomedical Engineering at the University of
Memphis, received the 2013 Junior Investigator Award from the American Journal of
Physiology (AJP) – Lung Cellular and Molecular Physiology for her paper “Hyperoxia
alters the mechanical properties of alveolar epithelial cells”.
The paper proposes a new mechanism by which excessive oxygen can lead to worse injury
in the lung. Dr. Roan explains, “We treat the lung cells and the membrane on which
they reside as a bilayered material, similar to for example paint on metal. We then
show that when the cells are exposed to excessive oxygen they become less deformable
and more susceptible to injury with a mechanical stretch loading, which is part of
lungs mechanical environment as we breathe or mechanically ventilate them.” Click to read the award winning submission. Click here to read an editorial written by Dr. Rolf D. Hubmayr.
“This award means a lot,” said Roan. “First, senior researchers in the field thought
of this work to be influential enough to nominate the paper. Next, the APS-Lung Cellular
and Molecular Physiology editors recognized the novelty in our work. Currently, we
are writing multiple manuscripts and grants on this biomechanical mechanism of injury
in the lung.”
Dr. Roan’s accomplishment was announced at the Trainee Highlights Breakfast at EB
conference on Sunday, April 27th. Dr. Roanacknowledges Dr. C.M. Waters, Dr. K.R. Wilhelm, and Dr. E. Eckstein.