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Dr. Esra Roan Awarded 2013 Junior Investigator Award

Dr. Golias

Dr. Esra Roan, Assistant Professor in Biomedical Engineering at the University of Memphis, received the 2013 Junior Investigator Award from the American Journal of Physiology (AJP) – Lung Cellular and Molecular Physiology for her paper “Hyperoxia alters the mechanical properties of alveolar epithelial cells”.

The paper proposes a new mechanism by which excessive oxygen can lead to worse injury in the lung.  Dr. Roan explains, “We treat the lung cells and the membrane on which they reside as a bilayered material, similar to for example paint on metal. We then show that when the cells are exposed to excessive oxygen they become less deformable and more susceptible to injury with a mechanical stretch loading, which is part of lungs mechanical environment as we breathe or mechanically ventilate them.” Click to read the award winning submission. Click here to read an editorial written by Dr. Rolf D. Hubmayr.

“This award means a lot,” said Roan. “First, senior researchers in the field thought of this work to be influential enough to nominate the paper. Next, the APS-Lung Cellular and Molecular Physiology editors recognized the novelty in our work.  Currently, we are writing multiple manuscripts and grants on this biomechanical mechanism of injury in the lung.”  

Dr. Roan’s accomplishment was announced at the Trainee Highlights Breakfast at EB conference on Sunday, April 27th. Dr. Roanacknowledges Dr. C.M. Waters, Dr. K.R. Wilhelm, and Dr. E. Eckstein.

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Last Updated: 4/29/14