Bernard Grisoni, Ph.D.
Schering Plough, Inc.
February 6, 2008
Manning Hall room 201
Refreshments will be served at 3:30pm in Manning Hall room 222
Abstract: The field of orthopaedic biomaterials is rapidly evolving. The recent advances in
science and technologies are placing us at a turning point of orthopaedic medicine.
Until a few decades ago, most of the biomaterials used in orthopedic surgery were
inert, mainly to either replace articulations or splint and fill bone defects.
These materials were selected for their physical strength, durability and biocompatibility.
Over the last 25 years, a plethora of new biomaterials and biomaterial composites
have emerged for the treatment of bone defects. Their goal is mainly to help the body
to repair itself by offering surfaces that facilitate bone cell migration and/or inducing
regeneration of specific tissues. To select these new biomaterials, new criteria were
developed such as osteointegration, bio-resorption, and bio-induction.
The outstanding advances in biology and genetic engineering are allowing new technologies
that may displace traditional orthopedic biomaterials. It is foreseeable in the near
future that humans will have new bones and joints grown in transgenic animals for
implantation, and genetic medicine will cure most degenerative diseases.
This presentation will broadly review current orthopeadic biomaterials and their applications,
the bioorthopedic material market and trends, and the types of new materials expected
in the near future.