CLION is based on an interdisciplinary and diverse research team comprising University of Memphis faculty and students including Mathematical Sciences (MSCI), Computer Science (CS), Electrical Engineering and Computer Engineering (EECE), as well as external collaborators and agencies including Air Force Research Laboratory (AFRL), Air Force Office of Scientific Research (AFOSR), Department of Energy (DoE), National Science Foundation (NSF), National Institutes of Health (NIH), NASA Jet Propulsion Laboratory (JPL), FedEx and others.

CLION provides University of Memphis students with research expertise in cutting-edge technologies, which provides them with a competitive advantage in the job market. CLION aims at becoming a regional and national center of excellence in large-scale networks and advanced intelligent optimization, capable of attracting and supporting large size multi-institution and multi-university research projects, and facilitating the commercialization of the products.