Cayuse IRB

Cayuse IRB ( provides visibility into the entire Institutional Review Board review and submission process while it simplifies the protocol creation process. Using your University of Memphis log in credentials, you will have 24/7 access to submission creation, IRB protocols, paperless electronic approvals – no waiting to receive approval docs - and management of IRB protocols from initial submission to close.


Cayuse IRB was ready for use on August 1, 2016.   Investigators are  REQUIRED to use Cayuse IRB for all protocol submissions. If you have tried opening Cayuse IRB and are unable to access it, or have any questions, please email


To access CayuseIRB go to, enter your UofM login and password, and select Cayuse IRB (Human Studies Compliance).

If you are a current student, faculty or staff member and have tried logging in to Cayuse and do not have access, please contact

General Cayuse Questions?  Contact or (901) 678-2705 .



  • Cayuse IRB for Researchers & Advisors (Quick-Start Tutorial)
  • Cayuse IRB for Researchers & Advisors (Screenshot Manual)
  • Cayuse IRB for Researchers & Advisors (Video Tutorial)
  • How to Submit, Modify, Renew, Report Incident, or Close a Legacy Study (Legacy Studies are past approved studies imported from the old IRB Database.) (Screenshot Manual)

For additional online assistance visit


Contact to schedule one-on-one training.