About Dr. Joel Bumgardner
Doctor of Philosophy in Biomedical Engineering
The University of Alabama at Birmingham, Birmingham, AL, August 1994
J. William Fulbright Fellowship, J. William Fulbright Foreign Scholarship Board/ US and Sweden, Department of Dental Materials Science, Faculty of Odontology, Umeå University, Umeå, Sweden, 1993-1994
Master of Science in Biomedical Engineering
The University of Alabama at Birmingham, Birmingham, AL, June 1989
Bachelor of Science in Materials Engineering
The University of Alabama at Birmingham, Birmingham, AL, December 1988
Bachelor of Science in Biology
Florida State University, Tallahassee, FL, April 1984
Professor, Biomedical Engineering Department, The University of Memphis, Memphis,
TN, July 2010-present
Adjunct Professor, School of Dentistry, The University of Tennessee Health Science Center, Memphis, TN. January 2010-present
Adjunct Professor, Department of Plastic Surgery, School of Medicine, The University of Tennessee Health Science Center, Memphis, TN, January 2010-present
Associate Professor, Biomedical Engineering Department, The University of Memphis, Memphis, TN, August 2004 – July 2010 (tenure awarded June 2008)
Adjunct Professor, Agricultural & Biological Engineering and Biomedical Engineering Program, Mississippi State University, Starkville, MS, August 2004 - 2010
Associate Professor, Biomedical Engineering Program, Mississippi State University, Starkville, MS, February 2001 – August 2004.
NIH International Fellowship, Division of International Training and Research and the Japan Society for the Promotion of Science, Short-Term Invitation Fellowship for Biomedical Research in Japan, Department of Biomaterials, Osaka University, Osaka, Japan, October - November 2000.
Associate Professor, Department of Agricultural and Biological Engineering, Mississippi State University, Starkville, MS, July 1998 – August 2004 (tenure awarded June 2000).
Assistant Professor, Department of Agricultural and Biological Engineering, Mississippi State University, Starkville, MS, Nov 1994 - June 1998
Interim Chair, Biomedical Engineering Department, The University of Memphis, Memphis,
TN, August 2012-June 2013
Co-coordinator Academic Programs, Biomedical Engineering Department, The University of Memphis, Memphis, TN, June 2006-present
Interim Department Head, Agricultural & Biological Engineering and Biomedical Engineering Program, Mississippi State University, Starkville, MS, January – August 2004
Honors and Awards
• 2017 Award for Outstanding Research, Herff College of Engineering, University of
• 2017 Award for Outstanding Service & Leadership, Society for Biomaterials
• Elected, Fellow of Biomaterials Science and Engineering, International College of Fellows of the International Union of Societies of Biomaterials and Engineering, 2016
• Memphis Area Joint Engineering Council, Achievement Award & Featured Engineer, Memphis, TN, 2015
• Faculty Inventor Recognition Award, University of Memphis, February 2014
• Herff College of Engineering Outstanding Instructor Award, University of Memphis, 2012
• 40 Engineers Making a Difference, UAB Engineering School 40th Anniversary Outstanding Alumni, 2011
• Elected, President Society for Biomaterials – USA 2012-2013
• Elected Fellow of American Institute of Medical & Biological Engineering, 2011
My area of research is in the dental/craniofacial and orthopaedic alloys, corrosion/degradation and surface modification/coatings, bone cell mechanics and in chitosan-based materials for implant coatings, bone tissue engineering/regenerative medicine engineering and drug delivery. Current active research is focused on design and development of chitosan-based materials and composites for; dental and orthopedic implant coatings, composites for bone grafts, injectable micro- and nano- particles for tissue scaffolds/templates and drug delivery, and wet-spinning, electrospinning and electrospraying of fibers/membranes/coatings. Research encompasses bulk and surface materials properties, in vitro and in vivo biocompatibility testing using wide range of cells including macrophage, fibroblast, osteoblast and endothelial cell cultures and rodent soft and hard tissue models.
N. Ghadri, K. Anderson, P. Adatrow, S. Stein, H. Su, F. Garcia-Godoy, A. Karydis, J. Bumgardner. Evaluation of Bone Regeneration of Simvastatin Loaded Chitosan Nanofiber Membranes in Rodent Calvarial Defects. Journal of Biomaterials and Nanobiotechnology, 9, 210-231. 2018 [doi: 10.4236/jbnb.2018.92012]
C. Wu, H. Su, A. Karydis, K.M. Anderson, N. Ghadri, S. Tang, Y. Wan, J.D. Bumgardner. Mechanically stable surface-hydrophobilized chitosan nanofibrous barrier membranes for guided bone regeneration Biomedical Materials, Volume 13, Number 1 (Biomed. Mater. 13 015004), 2017
G.S. McGraw, J. A. Jennings, T. Fujiwara, E. Masters, W. O. Haggard, J. D. Bumgardner. Chitosan Microspheres Cross-linked with Glyoxal for the Local Delivery of Antibiotics. Journal of Polymer Materials, Vol.34, No.1, Jan-March 2017. Vol. 34, Iss. 1, (Mar 2017): 305-317.
H. Su, K-Y Liu, A. Karydis, D. Abebe, C. Wu, K Anderson, N ghadri, P Adatrow, T. Fujiwara, J. D. Bumgardner. In vitro and In vivo evaluations of a novel post-electrospinning treatment to improve the fibrous structure of the chitosan membrane. Biomedical Materials [doi.org/10.1088/1748-605X/12/1/015003] 12(1):015003, 2016.
R.A. Kumar, A. Sivashanmugam, S. Deepthi, J.D. Bumgardner, S.V. Nair, R.. Jayakumar. Nano fibrin stabilized CaSO4 crystals incorporated injectable chitin composite hydrogel for enhanced angiogenesis and osteogenesis, Carbohydrate Polymers, [doi: 10.1016/j.carbpol.2015.11.074] 140:144-153, 2016.
J.A. Jennings, CM Wells, G.S. McGraw, D.A. Velasquez Pulgarin, M.D. Whitaker, R.L. Pruitt, J.D. Bumgardner. Chitosan coatings to control release and target tissues for therapeutic delivery. Therapeutic Delivery. [doi: 10.4155/tde.15.31] 6(7):855-71, 2015
P. Konofaos, D. Petersen, J Jennings, R. Smith, H. Doty, B. Reves, T. Guda, M. Appleford M, J.D. Bumgardner, R. Wallace. Evaluation of Amniotic Multipotential Tissue Matrix (AmnioMTM®) to augment healing of Demineralized Bone Matrix (DBM) in a rat calvarial model: A pilot study. Journal of Craniofacial Surgery, 26(4):1408-1412, 2014.
C. Wu, H. Su, S. Tang, J.D. Bumgardner. The stabilization of electrospun chitosan nanofibers by reversible acylation. Cellulose. 21(4):2549-2556, 2014.
J.O. Cooper, J.D. Bumgardner, J.A. Cole, R.S. Smith, W.O. Haggard. Co-cultured tissue-specific scaffolds for tendon/bone interface engineering. Journal of Tissue Engineering. [DOI: 10.1177/2041731414542294] 5: 1-11, 2014
A.C. Parker, J.K. Smith, B. Reves, J.A. Jennings, J.D. Bumgardner, W.O. Haggard. Effects of sodium acetate buffer on chitosan sponge properties and in vivo degradation in a rat intramuscular model. Journal of Biomedical Materials Research Part B: Applied Biomaterials. doi: 10.1002/jbm.b.33204] 103(2):387-96, 2015
J.M. Goodhart, J.O. Cooper, R.A. Smith, J.L. Williams, W.O. Haggard, J.D. Bumgardner. Design and validation of a cyclic strain bioreactor to condition spatially-selective scaffolds in dual strain regimes. Processes, 2:345-360, 2014.
H.A. Doty, M.R. Leedy, H.S. Courtney, W.O. Haggard, J.D. Bumgardner. Composite chitosan and calcium sulfate scaffold for dual delivery of vancomycin and recombinant human bone morphogenetic protein-2. Journal of Material Science Materials in Medicine 25(6):1449-59, 2014
A.J. Bavariya, P.A. Norowski Jr, K.M. Anderson, P.C. Adatrow, F. Garcia-Godoy, S.H. Stein, J.D. Bumgardner. Evaluation of biocompatibility and degradation of chitosan nanofiber membrane crosslinked with genipin. Journal of Biomedical Materials Research Part B: Applied Biomaterials. [doi: 10.1002/jbm.b.33090]. 102(5):1084-92, 2014
D.T. Nguyen, J.D. McCanless, M.M. Mecwan, A.P. Noblett, W.O. Haggard, R.A. Smith, J.D. Bumgardner. Balancing mechanical strength with bioactivity in chitosan-calcium phosphate 3D microsphere scaffolds for bone tissue engineering: air- vs. freeze-drying processes. Journal of Biomaterials Science Polymer Edition, [doi:10.1080/09205063.2012.735099] 24:1071-83, 2013.
M.R. Leedy, J.A. Jennings, W.O. Haggard, J.D. Bumgardner. Effects of VEGF-loaded chitosan coatings. Journal of Biomedical Materials Research Part A. [doi:10.1002/jbm.a.34745] 102:752-9, 2014.
B.T. Reves, J.D. Bumgardner, W.O. Haggard. Fabrication of crosslinked carboxy-methylchitosan microspheres and their incorporation into composite scaffolds for enhanced bone regeneration. Journal of Biomedical Materials Research Part B: Applied Biomaterials, [doi: 10.1002/jbm.b.32865], 101:630-9. 2013
P.A. Norowski, J. Babu, P.C. Adatrow, F. Garcia-Godoy, W.O. Haggard, J.D. Bumgardner, Antimicrobial activity of minocycline-loaded genipin-crosslinked nano-fibrous chitosan mats for guided tissue regeneration. Journal of Biomaterials and Nanobiotechnology, [doi 10.4236/jbnb.2012.324054] 3:528-532, 2012.
P.A. Norowski, W. Clem, P. Adatrow, T. Fujiwara, E. Eckstein, W.O. Haggard, J.D. Bumgardner, Novel naturally crosslinked electrospun nanofibrous chitosan mats for guided bone regeneration membranes: material characterization and cytocompatibility. Journal of Tissue Engineering and Regenerative Medicine [doi 10.1002/term.1648] 9 (5): 577-583, 2015.
P.A. Norowski, S. Mishra, P.C. Adatrow, W.O. Haggard, J.D. Bumgardner. Suture pullout strength and in vitro fibroblast and RAW 264.7 monocyte biocompatibility of genipin crosslinked nanofibrous chitosan mats for guided tissue regeneration. Journal of Biomedical Materials Research Part A. [doi: 10.1002/jbm.a.34224] 100(11): 2890-2896, 2012.
Y. Yuan, B.M. Chesnutt, W.O. Haggard, J.D. Bumgardner. Deacetylation of Chitosan: Material Characterization and in vitro Evaluation via Albumin Adsorption and Pre-Osteoblastic Cell Cultures Materials 4(8): 1399-1416, 2011 [doi: 10.3390/ma4081399].
B.T. Reves, J.A. Jennings, J.D. Bumgardner, W.O. Haggard Osteoinductivity Assessment of BMP-2 Loaded Composite Chitosan- Nano-Hydroxyapatite Scaffolds in a Rat Muscle Pouch. Materials 4(8), 1360- 1374, 2011 [doi:10.3390/ma4081360].
P.A. Norowski, R. Babu, H. Courtney, Y. Yang, Y. Yuan, W.O. Haggard, J.D. Bumgardner, Chitosan coatings containing antimicrobials; in vitro antibacterial and in vivo compatibility. Implant Dentistry 20:56-67, 2011.
M.M. Mecwan, G.E. Rapalo, S.R. Mishra, W.O. Haggard, J.D. Bumgardner. Effect of Molecular Weight of Chitosan Degraded by Microwave Irradiation on Lyophilized Scaffolds for Bone Tissue Engineering. Journal of Biomedical Materials Research Part A. 97A(1):66-73, 2011 [Epub ahead of print; 11 Feb 2011, doi: 10.1002/jbm.a.33029]
S.P. Noel, H.S. Courtney, J.D. Bumgardner, W.O. Haggard. "Chitosan Sponges to Locally Deliver Amikacin and Vancomycin: A Pilot In Vitro Evaluation" Clinical Orthopeadics and Related Research. 2010 Aug;468(8):2074-80. [Epub ahead of print, 30 March 2010].
B. Reves, J.D. Bumgardner, J. Cole, Y. Yang, W.O. Haggard, "Lyophilization to improve drug delivery for chitosan-calcium phosphate bone scaffold construct: A preliminary investigation" Journal of Biomedical Materials Research: Part B 90:1-10, 2009. 2009 Society for Biomaterials Award for Outstanding Research Paper, Masters Degree Category.
B.M. Chesnutt, Y. Yuan, K. Buddington, W.O. Haggard, J.D. Bumgardner, "Composite chitosan-nano- hydroxyapatite scaffolds induce osteocalcin production by osteoblasts in vitro and support bone formation in vivo," Tissue Engineering. 15:2571-2579, 2009. [Epub ahead of print 20 March 2009]
S.R. Jackson, K.C. Richelsoph, H.S. Courtney, J.C. Wenke, J.G. Branstetter, J.D. Bumgardner, W.O. Haggard, "Preliminary in vitro evaluation of an adjunctive therapy for extremity wound infection reduction: Rapidly resorbing local antibiotic delivery," Journal of Orthopaedic Research, 27:903-8, 2009. [Epub ahead of print 22 Dec 2008].
P.A. Norowski, Jr., J.D. Bumgardner, "Biomaterials and antibiotic strategies for peri-implantitis: A review" Journal of Biomedical Materials Research Part B 88:530-43, 2009. [Epub ahead of print 12 Aug 2008].
H.J. Martin, K.H. Schulz, J.D. Bumgardner, K.B. Walters, "An XPS Study on the Attachment of Triethoxsilylbutyraldehyde to Two Titanium Surfaces as a Way to Bond Chitosan" Applied Surface Science 254: 4599-4605, 2008 [DOI: 10.1016/j.apsusc.2008.01.066]
J.L. Cartner, J.L. Ong, W.O. Haggard, J.D. Bumgardner, "Stress Corrosion Cracking of an Aluminum Alloy Used in External Fixation Devices" Journal of Biomedical Medical Materials Research: Part B. 86:430-7, 2008. [DOI: 10.1002/jbm.b.31038]
B.M. Chesnutt, Y. Yuan, J.L Ong, Y. Yang, W.O. Haggard, J.D. Bumgardner, "Chitosan-nano-CaP composite microsphere constructs for bone tissue engineering" Journal of Biomedical Materials Research: Part A. 88:491-502, 2009 [DOI 10.1002/jbm.a.31878 ]
H.J. Martin, J.D. Bumgardner, K.B. Walters, K.H. Schulz, "An XPS Study on the use of 3-Aminopropyl-tri-ethoxy-silane to Bond Chitosan to a Titanium Surface" Langmuir, 23:6645-6651, 2007 [DOI: 10.1021/la063284v]
J.D. Bumgardner, B.M. Chesnutt, Y.Yuan, Y. Yang, M. Appleford, S.H. Oh, R. McLaughlin, S.H. Elder, J.L. Ong, "Integration of chitosan coated Ti in bone: in vivo study in rabbits" Implant Dentistry, 16:66-79, 2007.
Y. Yuan, B.M. Chesnutt, G. Utturkar, J.L Ong, Y. Yang, W.O. Haggard, J.D. Bumgardner, "Effect of Genipen Crosslinking on degradation and protein release from chitosan microspheres" Carbohydrate Polymers, 68:561-567, 2007 [DOI:10.1016/j.carbpol.2006.10.023].
W. Chen, Y. Liu, H.S. Courtney, M. Bettenga, C.M. Agrawal, J.D. Bumgardner, J.L. Ong, "In vitro anti- bacterial and biological properties of magnetron co-sputtered silver-containing hydroxyapatite coating" Biomaterials. 27:5512-5517, 2006
Y. Yang, N. Oh, Y. Liu, W. Chen, S. Oh, M. Appleford, S. Kim, K. Kim, S. Park, J.D. Bumgardner, W. Haggard, J. Ong "Enhancement of osseointegration using surface modified titanium implant" Journal of Minerals, Metals, and Materials; Surface Modification in Bioapplications 58:71-76, 2006
V.M. Hamilton, Y. Yuan, D. Rigney, A. Puckett, J.L. Ong, Y. Yang, S.H. Elder, J.D. Bumgardner, "Characterization of chitosan films and effects on fibroblast cell attachment and proliferation", Journal of Materials Science-Materials in Medicine, 17:1373-1381, 2006.
X.F. Walboomers, S.E. Elder, J.D. Bumgardner, J.A. Jansen, "Hydrodynamic compression of young and adult rat osteoblast-like cells on titanium fiber mesh" Journal of Biomedical Materials Research, 76A(1):16-24, 2006. [Epub ahead of print, 25 Oct 2005, DOI 10.1002/jbm.a.30304].
H.-Y. Lin, J.D. Bumgardner, "Role of Macrophage Cells in Corrosion of Co-Cr-Mo alloys," Journal of Orthopaedic Research, 22(6):1231-1236, 2004
X.F. Walboomers, E.M. Habraken, B. Feddes, L.C. Winter, J.D. Bumgardner, J.A. Jansen, "Stretch mediated response of osteoblast like cells cultured on titanium coated substrates in vitro" Journal of Biomedical Materials Research, 69A:131-139, 2004
H.-Y. Lin, J.D. Bumgardner, "Changes in Surface Oxides of Co-Cr Alloys by Macrophage Cells", Biomaterials, 25:1233-1238, 2004
J.D. Bumgardner, R. Wiser, S. H. Elder, R. Jouett, Y. Yang and J. L. Ong, "Protein Absorption and Osteoblast Cell Attachment to Titanium and Chitosan Coated Titanium" Journal of Biomaterials Science:Polymer Edition, 14:1401 -1410, 2003
H.-Y. Lin, J.D. Bumgardner, "Changes in Surface Oxides Ti-6Al-4V Alloys by Macrophage Cells", Applied Surface Science, 225:21-28, 2004 (E-pub ahead of print 19 November 2003: doi:10.1016/j.apsusc.2003.09.027)
L.C. Winter, X.F. Walboomers, J.D. Bumgardner, J.A. Jansen, "Intermittent vs. Continuous Stretching Effects on Osteoblast-like Cells In-Vitro" Journal Biomedical Materials Research, 67A(4):1269-1275, 2003
J.D. Bumgardner, R. Wiser, P. Bergin, B. Chesnutt, M. Marini, V. Ramsey, P.D. Gerard, S.H. Elder, J.A. Gilbert, "Chitosan: Potential Use as a Bioactive Coating for Orthopaedic and Craniofacial/Dental Implants" Journal of Biomaterials Science:Polymer Edition, 14:423-438, 2003 (2003 MAFES Award Scientific Merit)
J.D. Bumgardner, H.Y. Lin, S.H. Parker, L.D. Zardiackas, "Effects of Macrophage Cells on Corrosion of 316L Stainless Steel" In: ASTM STP 1438, Stainless Steels for Medical and Surgical Applications, eds Winter and Nutt, ASTM International: West Conshohocken, PA. pp137-153, 2003
Books and Chapters
J.A. Jennings, J.D. Bumgardner (editors), Chitosan Based Biomaterials Volume 2- Tissue Engineering and Therapeutics. Woodhead Publishing, 2017.
J.A. Jennings, J.D. Bumgardner (editors), Chitosan Based Biomaterials Volume 1- Fundamentals. Woodhead Publishing, 2017.
A. Anith, N.S. Rejinold, J.D. Bumgardner, S.V. Nair, R. Jayakumar, Approaches for functional modification or crosslinking of chitosan. In: Chitosan-based Systems for Biopharmaceuticals: Delivery, targeting and polymer therapeutics. Editors B. Sarmento, J. Das Neves., J Wiley & Sons Ltd. pp 107-124, 2012
C. Szpalski, G.F. Rogers, M. McRae, J.D. Bumgardner, S.M. Warren. Biomaterials and Their Application in Craniomaxillofacial Surgery. In: Comprehensive Biomaterials, Eds: P. Ducheyne, K.E. Healy, D.W. Hutmacher, D.W. Grainger, C.J. Kirkpatrick, Elsevier, Vol. 6:325-341, 2011
M.R. Leedy, H. Martin, J.A. Jennings, P.A. Norowski, W.O. Haggard, J.D. Bumgardner. Use of chitosan as a bioactive implant coating for bone implant applications. In: Advances in Polymer Science: Chitosan for Biomaterials II, Special Issue Editors: R. Jayakumar, M. Prabaharan, R.A.A. Muzzarelli, Springer. Vol 224:129-165, 2011 [doi: 10.1007/12_2011_115]
Recent Invited Lectures
"Electrospun chitosan membranes for local delivery of therapeutics" Plenary Lecture, 14th International Chitin and Conference, Osaka, Japan, August 2018 "Characterization of Chitosan Matters" Plenary Lecture, 11th Asia Pacific Chitin and Chitosan Symposium, Kochi, Kerala, India, September 2016
"Development of Modified Chitosans for Guided Bone Regeneration", Invited Lecture, Asia Polymer Association International Conference on Advanced Polymers, biomaterials, bioengineering & Nano Drug Delivery, Flic-En-Flac, Mauritius, September 2016.
"Electrospun chitosan membranes for guided bone regeneration" Plenary Lecture, Indo-Australian Conference on Biomaterials, Tissue Engineering, Drug Delivery Systems & Regenerative Medicine (BiTERM 2015), Chennai India, February 2015.
"Chitosan – a versatile material for biomedical implant applications" Biomedical Engineering Materials and Applications (BEMA) Roundtable Committee Meeting, National Research Council of the National Academies of Science and Engineering and the Institute of Medicine. The National Academies Keck Center, Washington, DC, April 2014.
"Chitosan implant coatings for dental/craniofacial and orthopedic applications" 10th International Conference of the Asian Pacific Chitin Chitosan Symposium Yonago City, Japan, October 2013.
"Chitosan-based Materials for Bone Implant & Tissue Engineering Applications" Medtronic Lecture Series,Medtronic, Memphis, TN, October 2012
National Institutes of Health, 1R01DE026759-01 "Chitosan Guided Bone Regeneration Membranes for Dual Local Delivery of Simvastatin and Raspberry Ketone" April 2017 – March 2022, (role: Principal Investigator)
National Institutes of Health, "Investigating a flexible degradable local antibiotic delivery system" Jan 2015 – Dec 2020, (role: co-Investigator; Principle investigator: Jennings)
Dual Action Coating for Infection Prevention and Osseointegration, FedEx Institute of Technology Innovation Fund. Sept 2015 – June 2018 (role: Principal Investigator)