Matthew Smeltzer, PhD

About Matthew Smeltzer, PhD
Matthew P. Smeltzer, PhD, MStat, is an Associate Professor of Epidemiology and Biostatistics and University Research Professor. He is a 2019 Fellow of the National Cancer Institute (NCI) Training Institute for Dissemination and Implementation Research in Cancer. Dr. Smeltzer's primary research interests include clinical outcomes, quality of care, disease surveillance, and implementation science in cancer and sickle cell disease. His work is currently funded by the National Cancer Institute (NCI), National Heart, Lung and Blood Institute (NHLBI), and the US Centers for Disease Control and Prevention (CDC). Dr. Smeltzer has more than 120 peer-reviewed publications, with additional research experience in childhood cancer, ovarian cancer, breast cancer, immunology, anesthesiology, and biomedical engineering. He enjoys teaching Epidemiologic Methods, Applied Biostatistics, and training doctoral students.
Dr. Smeltzer is active in the International Association for the Study of Lung Cancer (IASLC) and Principal Investigator of the Tennessee sickle cell disease surveillance program (SCDC) funded by the CDC. He is the quantitative lead for the Mid-South Quality of Surgical Resection (MS-QSR) and the Detecting Early Lung Cancer (DELUGE) in the Mississippi Delta cohorts. He also serves on the steering committee for the St. Jude Sickle Cell Clinical Research and Intervention Program (SCCRIP) cohort. Prior to joining the University of Memphis faculty, Dr. Smeltzer spent 11 years in the Department of Biostatistics at St. Jude Children's Research Hospital and is an Accredited Professional Statistician by the American Statistical Association.
Education
- PhD, Epidemiology, School of Public Health, University of Memphis, Memphis, TN
- MStat, Statistics, University of Florida, Gainesville, FL
- BS, Mathematics (cum laude), Harding University, Searcy, AR
Research Interests
- Cancer
- Sickle cell disease
- Implementation science
- Disease Surveillance
- Bias analysis
- Statistics for epidemiology
Selective Publications
- Matthew P. Smeltzer, Meredith A. Ray, Nicholas R. Faris, Raymond U. Osarogiagbon. Genie Out of the Bottle: Is There a Role for Gene-Gene Interactions in Early Detection of Lung Cancer?. Journal of Thoracic Oncology. Volume 17, Issue 8, 2022; Pages 946-948. ISSN 1556-0864. https://doi.org/10.1016/j.jtho.2022.05.012.
- Upal Basu Roy, Anne-Marie Baird, Andrew Ciupek, Jesme Fox, Eugene Manley, Kim Norris, Giorgio V. Scagliotti, Heather A. Wakelee, Tetsuya Mitsudomi, Russell J. Clark, Renee Arndt, Fred R. Hirsch, Paul A. Bunn, Matthew P. Smeltzer. Impact of the Coronavirus Disease 2019 Pandemic on Global Lung Cancer Clinical Trials: Why It Matters to People With Lung Cancer. JTO Clinical and Research Reports. Volume 3, Issue 2, 2022;100269. ISSN 2666-3643. https://doi.org/10.1016/j.jtocrr.2021.100269.
- Matthew P. Smeltzer, Wei Liao, Nicholas R. Faris, Carrie Fehnel, Jordan Goss, Catherine J. Shepherd, Rodolfo Ramos, Talat Qureshi, Ayesha Mukhopadhyay, Meredith A. Ray, Raymond Uyiosa Osarogiagbon. Potential Impact of Criteria Modifications on Race and Sex Disparities in Eligibility for Lung Cancer Screening. Journal of Thoracic Oncology. Volume 18, Issue 2, 2023; Pages 158-168. ISSN 1556-0864. https://doi.org/10.1016/j.jtho.2022.09.220.
- Wogksch Matthew D., Finch Emily R., Nolan Vikki G., Smeltzer Matthew P., Mzayek Fawaz, Goodenough Chelsea G., Pui Ching-Hon, Inaba Hiroto, Mulrooney Daniel A., Kaste Sue C., Brinkman Tara M., Lanctot Jennifer Q., Srivastava Deo Kumar, Jefferies John L., Armstrong Gregory T., Robison Leslie L., Hudson Melissa M., Ness Kirsten K. Energy cost of walking in obese survivors of acute lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort. Frontiers in Pediatrics,10, 2022. ISSN 2296-2360. doi.10.3389/fped.2022.976012.
- Allison P. Plaxco, Jennifer M. Kmet, Vikki G. Nolan, Michelle A. Taylor, Matthew P. Smeltzer. Real-World Association Between mRNA Vaccination and Infection From the Omicron Strain of SARS-CoV-2: A Population-Level Analysis. AJPM Focus, Volume 1, Issue 1, 2022; 100010. ISSN 2773-0654. https://doi.org/10.1016/j.focus.2022.100010.
- Smeltzer MP, Ray MA. Statistical considerations for outcomes in clinical research: A review of common data types and methodology. Experimental Biology and Medicine. 2022;247(9):734-742. doi:10.1177/15353702221085710
- Matthew P. Smeltzer, Meredith A. Ray, Nicholas R. Faris, Meghan B. Meadows-Taylor, Fedoria Rugless, Courtney Berryman, Bianca Jackson, Carrie Fehnel, Alicia Pacheco, Laura McHugh, Edward T. Robbins, Kenneth D. Ward, Lisa M. Klesges, and Raymond U. Osarogiagbon. Prospective Comparative Effectiveness Trial of Multidisciplinary Lung Cancer Care Within a Community-Based Health Care System. JCO Oncology Practice 2023 19:1, e15-e24.
- Matthew P. Smeltzer, Giorgio V. Scagliotti, Heather A. Wakelee, Tetsuya Mitsudomi, Upal Basu Roy, Russell C. Clark, Renee Arndt, Clayton D. Pruett, Karen L. Kelly, Peter Ujhazy, Melissa L. Johnson, Yesim Eralp, Carlos H. Barrios, Fabrice Barlesi, Fred R. Hirsch, Paul A. Bunn. International Association for the Study of Lung Cancer Study of the Impact of Coronavirus Disease 2019 on International Lung Cancer Clinical Trials. Journal of Thoracic Oncology. Volume 17, Issue 5, 2022; Pages 651-660. ISSN 1556-0864. https://doi.org/10.1016/j.jtho.2022.01.017.
- Osarogiagbon RU, Liao W, Faris NR, Meadows-Taylor M, Fehnel C, Lane J, Williams SC, Patel AA, Akinbobola OA, Pacheco A, Epperson A, Luttrell J, McCoy D, McHugh L, Signore R, Bishop AM, Tonkin K, Optican R, Wright J, Robbins T, Ray MA, Smeltzer MP. Lung Cancer Diagnosed Through Screening, Lung Nodule, and Neither Program: A Prospective Observational Study of the Detecting Early Lung Cancer (DELUGE) in the Mississippi Delta Cohort. J Clin Oncol. 2022 Jul 1;40(19):2094-2105. doi: 10.1200/JCO.21.02496. Epub 2022 Mar 8. PMID: 35258994; PMCID: PMC9242408.
- Meghan B. Meadows-Taylor, Nicholas R. Faris, Matthew P. Smeltzer, Meredith A. Ray, Carrie Fehnel, Olawale Akinbobola, Folabi Ariganjoye, Anita Patel, Alicia Pacheco, Anurag Mehrotra, Roy Fox, Robert Optican, Keith Tonkin, James Machin, Jeffrey Wright, Edward T. Robbins, Raymond U. Osarogiagbon. The Relative Survival Impact of Guideline-Concordant Clinical Staging and Stage-Appropriate Treatment of Potentially Curable Non-Small Cell Lung Cancer: Chest. Volume 162, Issue 1, 2022; Pages 242-255. ISSN 0012-3692. https://doi.org/10.1016/j.chest.2022.01.046.
