PI Millionaires
Andrew Liu, Biological Sciences
Name of projects/grants
Cellular and molecular basis of circadian behavior
Molecular, cellular, physiological mechanisms of the mammalian circadian clock.
Sponsoring Agencies:
National Science Foundation (NSF)
National Institutes of Health (NIH)
Time Frame of Projects:
Project 1: 2009-2013
Project 2: 2012-2017
Collaborators:
Project 1: Hiroki R. Ueda (University of Tokyo), Carrie L. Partch (University of California,
Santa Cruz).
Project 2: John B. Hogenesch (University of Pennsylvania), Nahum Sonenberg (University
of McGill).
Summary of Research Efforts:
The major focus of my lab is the biochemical and molecular basis of various circadian
rhythms in physiology and behavior, including, most obviously, our sleep/wakefulness
cycle. We use mice and cultured cells as model systems and employ highly integrated
approaches in our research, including molecular biology, biochemistry, genetics, genomics,
and pharmacology. Leveraging our expertise, we aim to probe the biochemical and structural
basis of circadian behavior, and to identify novel genes and networks, as well as
small molecules/drugs, that modulate clock function. Recently we also begin to investigate
the physiology of blood pressure regulation and pathophysiology of hypertension, centering
on circadian rhythm of blood pressure, asleep hypertension and chronotherapeutics.
Scientifically, our goal is to fill in the gaps in knowledge about the molecular and
cellular processes connecting genes to behavior, and to elucidate how the molecular
clocks regulate behavior, physiology, and metabolism. Ultimately, we hope to gather
sufficiently detailed knowledge to effectively modulate our daily timekeeping system
to enhance body fitness and improve our overall wellbeing
James Murphy, Psychology
Project/Grant Information for James G. Murphy
Name of projects/grants
1) A Behavioral Economic Supplement for Alcohol Use Disorder Treatment (NIH/NIAAA)
2) Prevention of Alcohol-related Incidents in the U.S. Air Force (NIH/DOD)
3) Improving Brief Alcohol Interventions with a Behavioral Economic Supplement (NIH/NIAAA
CRAN supplement to develop/evaluate intervention for marijuana use)
4) Effective On-Demand Motivational Interviewing Powered by AutoTutor Conversation
Engine (Xerox Corporation)
5) Improving Brief Alcohol Interventions with a Behavioral Economic Supplement (NIH/NIAAA)
6) Protective Behavioral Strategies and Brief Alcohol Interventions (NIH/NIAAA)
7) Enhancing College ETOH Interventions with a Substance-Free Activity Supplement
(NIH/NIAAA)
8) Predictors of Smokeless Tobacco and Dual Use in the US Military (NIH)
9) Behavioral Economic Moderators of Brief Alcohol Interventions in a Diverse Sample
of College Students (Alcohol Research Foundation)
10) Informing Public Policy on Tobacco Taxation via Cigarette Demand Curve Analysis
(Robert Wood Johnson Foundation)
Time Frame of Projects
1) 2015- 2018
2) 2014 – 2019
3) 2014 – 2016
4) 2014 – 2017
5) 2012 – 2017
6) 2009 – 2012
7) 2008 – 2011
8) 2010- 2011
9) 2008 – 2010
10) 2007 – 2010
Primary Collaborators
1) Lidia Meshesha (University of Memphis), Dr. Ed Wise (Mental Health Resources)
2) Drs. Robert Klesges (PI, University of Tennessee Health Sciences), Meghan McDevitt-Murphy,
(University of Memphis)
3) Brian Borasri, (Brown University)
4) Drs. Xiangen Hu (PI) and Whelan (University of Memphis)
5) Drs. Matthew Martens (University of Missouri), Brian Borsari (Brown University),
and Ashley Dennhardt (University of Memphis)
6) Dr. Matthew Martens (PI, University of Missouri)
7) Drs. Matthew Martens (University of Missouri), Nancy Barnett (Brown University),
Brian Borsari (Brown University), and Suzanne Colby (Brown University)
8) Dr. Robert Klesges (PI, University of Tennessee Health Sciences)
9) Matthew Martens (University of Missouri)
10) James MacKillop (PI, McMaster University)
Lan Wang, Computer Science
Greg Washington, Social Work
7/2015-9/2016
Tennessee Board of Regents, Funding Award- $40,000
Expanding assets and Steering Initiative
10/2015-9/2019
Substance Abuse and Mental Health Services Administration (SAMSHA) thru Meharry Medical
College, Funding Award- $73,503
Screening, Brief Intervention, and Referral to Treatment (SBIRT) Training Grant
10/2014-9/2015
Substance Abuse and Mental Health Services Administration (SAMSHA) thru TN Dept. Mental
Health and Developmental Disabilities, Funding Award- $36,421
Evaluation of Just Care Family Network System of Care
10/2014-9/2015
Substance Abuse and Mental Health Services Administration (SAMSHA), Funding Award-$71,584
The Memphis Substance-Using Women's Action Team (SWAT)
10/2014-9/2015
Tennessee Board of Regents, Funding Award- $40,000
Students Helping Students
Completed Research Support
10/2013-9/2014
Substance Abuse and Mental Health Services Administration (SAMSHA), Funding Award-$72,052
The Memphis Substance-Using Women's Action Team (SWAT)
10/2013-9/2014
Substance Abuse and Mental Health Services Administration (SAMSHA) Funding thru TN
Dept. Mental Health and Developmental Disabilities Funding Award- $74,379
Evaluation of Just Care Family Network System of Care
10/2012-9/2013
Substance Abuse and Mental Health Services Administration (SAMSHA) Funding thru TN
Dept. Mental Health and Developmental Disabilities Funding Award- $229,565
Evaluation of Just Care Family Network System of Care
7/2012-9/2012
Substance Abuse and Mental Health Services Administration (SAMSHA) Funding thru TN
Dept. Mental Health and Developmental Disabilities Funding Award- $110,412
Evaluation of Just Care Family Network System of Care
10/2011-6/2012
Substance Abuse and Mental Health Services Administration (SAMSHA) Funding thru TN
Dept. Mental Health and Developmental Disabilities Funding Award-$294,624
Evaluation of Just Care Family Network System of Care
7/2011-9/2011
Substance Abuse and Mental Health Services Administration Funding thru TN Dept. Mental
Health and Developmental Disabilities Funding Award-$99,534
Evaluation of Just Care Family Network System of Care
7/2011-12/2012
Strengthening Communities Initiative Award -$6250
Evaluation of Expanding Assets and Strengthening Initiative
6/2010-5/2011
City of Memphis of Funding Award -$226,700
Evaluation of Memphis Ambassadors Program